- In studies, almost 90% of patients showed improvement within 1 week3
- 73% of adult patients showed moderate improvement or better after 12 weeks using Protopic 0.1% compared with 21% with vehicle1
- 73% of pediatric patients showed moderate improvement or better after 12 weeks using Protopic 0.03% compared with 26% with vehicle1
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| *Eczema Area and Severity Index7 |
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References
1. Data on file. Fujisawa Healthcare, Inc., Deerfield, Ill.
2. Hanifin JM, et al. J Am Acad Dermatol. 2001;44(suppl):S28-S38.
3. Reitamo S, et al. Arch Dermatol. 2000;136:999-1006.
4. Protopic® (tacrolimus) Ointment full prescribing information. Deerfield, Ill: Fujisawa Healthcare, Inc.; 2000.
5. Paller A, et al. J Am Acad Dermatol. 2001;44(suppl):S47-S57.
6. Leung D, et al. Proceedings of American Academy of Dermatology. February 2002; New Orleans, La.
7. Hanifin JM, et al. Exp Dermatol. 2001;10:11-18.
8. Kang S, et al. J Am Acad Dermatol. 2001;44(suppl):S58-S64
Important Information
For short-term and intermittent long-term therapy in patients with moderate to severe atopic dermatitis who should avoid the potential risks of conventional therapies or are not adequately responsive to conventional therapies. Both 0.03% and 0.1% ointment can be used for adults. In children aged 2 to 15 years, only Protopic 0.03% is indicated.
The most common adverse events associated with the use of Protopic Ointment included the sensation of skin burning, pruritus, flu-like symptoms, and headache, and it is contraindicated in patients who are hypersensitive to tacrolimus or any of the other ingredients of Protopic.
Protopic Ointment should not be used with occlusive dressings.
Skin infections should be cleared prior to application, and there may be an increased risk of certain skin infections. Patients should minimize or avoid natural or artificial sunlight exposure.